ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0019.12-3 | New data on complications of children with T2DM | ESPEYB19

12.3. Long-term complications in youth-onset type 2 diabetes

P. TODAY Study Group, Bjornstad P, Drews KL, Caprio S, Gubitosi-Klug R, Nathan DM, Tesfaldet B, Tryggestad J, White NH, Zeitler

The New England Journal of Medicine 2021;385(5):416-26. doi: 10.1056/NEJMoa2100165Brief Summary: This multicenter observational study assessed the cumulative incidence of diabetic complications in 500 adolescents with Type 2 diabetes (T2DM), followed from 2011 to 2020. After only 13 years from T2DM diagnosis, higher complication rates were observed than those reported for pediatric patients wit...
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ey0020.10-7 | New Drugs for Children with T2DM | ESPEYB20

10.7. Maternal diabetes in youth-onset type 2 diabetes is associated with progressive dysglycemia and risk of complications

RD Shah , SD Chernausek , L El Ghormli , ME Geffner , J Keady , MM Kelsey , R Farrell , B Tesfaldet , JB Tryggestad , M Van Name , E Isganaitis

Brief summary: This analysis of data from the TODAY study examined the impact of parental diabetes on outcomes in young individuals with T2D during over 12 years of follow-up. This novel observation demonstrates that parental diabetes affects not only earlier T2D onset, but also more rapid long-term progression and more complications.Comment: This study showed that T2D diagnosis in either parent was associated with younger age at T2D diagnosis in their c...
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Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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